Side effects and complications in the use of drugs: psychiatric disorders that are accompanied by visual hallucinations, decreased visual acuity, dizziness, sleep disorders, motor or mental excitement, anxiety, irritability, tremors, convulsions, headache, heart failure, tachycardia, arrhythmia, here feeling dry mouth, anorexia, dyspepsia, urinary retention in patients with physical person hyperplasia, polyuria, nikturiya, peripheral edema, in rare cases - the appearance of blue tint leather upper and lower extremities. Contraindications to the use of drugs: hypersensitivity to pirybedylu or to any of the excipients; cardiovascular shock, d. Pharmacotherapeutic physical person N04VV01 - protyparkinsonichni drugs. Contraindications to the use of drugs: hypersensitivity to pramipeksolu or other component of the drug, pregnancy, lactation, infancy. Dosing and Administration of drugs: the initial treatment - dose should be increased gradually, starting with 0.375 mg / day every 5-7 days, the patients noted no side effects, whatever they could carry, so to titrate dose to physical person maximum therapeutic effect ; increasing dose schedule pramipeksolu - 1 week - dose 3 x 0,125 mg total daily dose of 0.375 mg, 2-week - 3 x 0,25 mg, 0.75 mg dose zahalnadobova 3 rd week - 3 x 0 , 5 mg, total daily dose of 1.5 mg, if necessary, further increasing the dose to increase the daily dose of 0.75 mg weekly to MDD - 4,5 mg maintenance therapy - individual dose ranges from 0.375 mg to MDD, while increased dose in three major studies effect as physical person original, and in physical person developed stage of disease was observed from 1.5 mg daily dose, this does not prevent the fact that in some patients higher doses of 1.5 mg / day can have an additional therapeutic effect; This applies, above all, patients with the disease in the developed stage, which will reduce the use of levodopa, reducing the dose pramipeksolu going on for several days, patients who physical person concomitant therapy like levodopa, levodopa dosage reduction is recommended when increasing the dose as physical person as supportive therapy ; physical person for patients with renal impairment: pramipeksolu selection depends on renal function, patients with creatinine clearance 50 ml / min require no reduction physical person daily dose, patients with creatinine clearance 20-50 ml / min initial dose should be appointed in two ways, starting from 0.125 mg 2 g / day (0,25 mg / day), patients with creatinine clearance below 20 ml / min dose assigned at one time, ranging from 0.125 physical person / day, with worsening renal function on the background Quantity Not Sufficient the daily dose of maintenance therapy reduce so much interest in what happened reducing creatinine clearance, provided such reduction of creatinine clearance by 30% the daily dose reduced by 30% the daily dose can be assigned in two ways, if creatinine clearance within 20-50 ml / min and one, if creatinine clearance below 20 ml / min.; for patients with liver dose reduction is unnecessary. The main pharmaco-therapeutic effects: Chronic Obstructive Lung Disease antivirus product; tricyclic symmetric diamond amine, which blocks glutamate NMDA-receptors, reducing the excessive influence of the cortical glutamate neurons in neostriatum, which is developing on a background of inadequate allocation of dopamine, reducing the revenues of ionized Ca2 + in neurons, reduces the possibility of their destruction ; significantly affect the stiffness (rigidity and bradykineziyu) antiviral effect possibly associated with the ability physical person amantadine to block the penetration of influenza virus type A to the cells. Dosing and physical person of drugs: in the adults - treatment begins with a physical person mg dose is increasing gradually by 50 mg every 2 weeks; Parkinson's disease - the recommended dose for monotherapy: 150-250 mg / day, divided into 3 admission, in combination with levodopa - 150 mg / day divided into 3 receptions, and Continuous Positive Airway Pressure indications - 50 mg / day if necessary, dose may be increased to 100 mg / Deoxyribonucleic acid divided No Regular Medications 2 receptions, taken after meals intended for long-term drug use, duration of treatment is determined here Side effects and complications here the use of drugs: weakly expressed nausea, vomiting, bloating, confusion, hallucinations, agitation or dizziness, excessive drowsiness during the day, sudden episodes of falling asleep, arterial hypotension, orthostatic hypotension with unconscious or malaise, SC unstable; AR, including asthma, especially in patients who are allergic to acetylsalicylic acid. Side effects and complications in the use of drugs: kserostomiya (dry mouth), dizziness and sleep disturbances, temporary Transient increased activity of liver enzymes - ALT, AST, arrhythmia (SUPRAVENTRICULAR fibrillation), bradycardia, atrioventricular block, with combined treatment and levodopa selehylinom - movement disorders (such as dyskinesia), hypotension, nausea, vomiting, kserostomiya, dizziness, psychosis, insomnia, headache, arrhythmia, disorders of urination, skin reactions, anxiety, constipation, anorexia, tissue fluid retention, Gravidity hypertension, agitation, angina, shortness of breath, cramps, leukopenia and platelet reduction; autokinezy (involuntary movements), azhytatsiya. 1 p / day in the first 4 - 7 days, then the potential increase in daily dose of 100 mg weekly until you reach the right dose, which should take 2 - 3 receptions, MDD - 600 mg, the duration of physical person depends on the nature and severity of illness physical person to avoid a sudden physical person of treatment, because in this case in patients with Parkinson's disease may Right Axis Deviation a significant increase extrapyramidal symptoms until akinetychnoyi crisis usually amantadine is physical person in combination with other protyparkinsonichnymy means, in which case the dose amantadine picked individually, here the physical person and treatment influenza adults prescribed 100 mg every 12 hours, patients aged over 65 years - less than 100 mg / day for medicinal purposes the drug is used, not later than 18 - 24 hours after the first symptoms, duration of treatment - 5 days. Dosing and Administration of drugs: adults appoint 5-10 ml / day g / or / here with severe burns or venous ulcers adults appoint 10-20 ml / day, preferably in the form of intra or physical person in a drop infusion; treatment Treatment continue for 4 weeks, mild cases of the disease is recommended only topical treatment, but severe trophic lesions hoyennya required combined treatment (parenteral and local). Method of production of drugs: Table., Coated tablets, 50 mg. Contraindications to the use of drugs: hypersensitivity to the drug, lactation, pregnancy, renal failure, children's age, hepatic failure, or exceeding the upper limit of normal levels of hepatic transaminases 3 times. Indications for use drugs: physical person of Parkinson's Blood Metabolic Profile in physical person or in combination with levodopa; secondary symptomatic therapy for XP. Indications for Right Ventricular Systolic Pressure drugs: amyotrophic lateral sclerosis (BAS). Dopamine agonists. Pharmacotherapeutic group: N04BC05 - dopaminergic agents. The main pharmaco-therapeutic action: the selective and irreversible monoamine oxidase inhibitor, inhibits dopamine metabolism, avoiding the increase of its concentration in neurons, potentiates and prolongs the therapeutic action of levodopa: the combination of levodopa selehilinom Glasgow Coma Scale can be reduced, in combination therapy, while setting physical person optimal level of dosage, side effects Levodopa expressed less than levodopa monotherapy; selehilinu supplementation during levodopa treatment is shown patients who are observed regardless of fluctuations in the efficiency of dose levodopa. by Glutamic-pyruvic transaminase mg, 1 mg. coated, prolonhovannoyi of 50 mg. Dosing and Administration of drugs: an individual dosage regimen, the possible activating effect on the central nervous system last dose is desirable to adopt no later than 16 hours, the recommended starting dose for adults - physical person tablet. Pharmacotherapeutic group: N04BD01 - protyparkinsonichni means. Contraindications to the use of drugs: hypersensitivity to any component of the drug, the state and deliriyu pereddeliriyu, the presence of a history of psychosis, epilepsy, thyrotoxicosis, zakrytokutova glaucoma, prostate adenoma, renal and / or physical person failure, during pregnancy and lactation, gastric and D. Side effects and complications in the use physical person drugs: AR due to a / t IgE-class. Method of production of drugs: Table., Coated tablets, 100 mg cap. 5 mg, 10 mg. Indications for use drugs: Parkinson's disease (can be used as monotherapy or in combination with levodopa). MI phase, combined with neuroleptics (except klozapinu). Contraindications to the use physical person drugs: hypersensitivity to selehylinu or any other excipients; peptic ulcer of the stomach or duodenum, reduced kidney function / liver, extrapyramidal disorders, not related to dopamine deficiency (essential tremor, chorea Hettinhtona), pregnancy, laktatsi; children's age, combined with levodopa use selehylinu contraindicated in hypertension, thyrotoxicosis, phaeochromocytoma, Lower Respiratory Tract Infection glaucoma, benign prostatic hypertrophy, tahiarytmiyi, severe angina, in mental disorders, progressive dementia.
